Allele Loss and Down-Regulation of Heparanase Gene Are Associated with the Progression and Poor Prognosis of Hepatocellular Carcinoma

OBJECTIVES: The role of heparanase (HPSE) gene in cancers including hepatocellular carcinoma (HCC) is currently controversial. This study was aimed at investigating the impact of genetic alteration and expression change of HPSE on the progression and prognosis of HCC. METHODS: The HPSE gene was stud...

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Detalles Bibliográficos
Autores principales: Huang, Guo-Liang, Li, Bin-Kui, Zhang, Mei-Yin, Wei, Rong-Rong, Yuan, Yun-Fei, Shi, Ming, Chen, Xiao-Qian, Huang, Long, Zhang, Hui-Zhong, Liu, Wanqing, Huang, Bi-Jun, Li, Honghua, Zheng, Xiao-Feng, Luo, Xian-Rong, Wang, Hui-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432106/
https://www.ncbi.nlm.nih.gov/pubmed/22952874
http://dx.doi.org/10.1371/journal.pone.0044061

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