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Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein

BACKGROUND: Extracellular high mobility group box 1 (HMGB1) protein can operate in a synergistic fashion with different signal molecules promoting an increase of cell Ca(2+) influx. However, the mechanisms responsible for this effect of HMGB1 are still unknown. PRINCIPAL FINDINGS: Here we demonstrat...

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Detalles Bibliográficos
Autores principales: Pedrazzi, Marco, Averna, Monica, Sparatore, Bianca, Patrone, Mauro, Salamino, Franca, Marcoli, Manuela, Maura, Guido, Cervetto, Chiara, Frattaroli, Daniela, Pontremoli, Sandro, Melloni, Edon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432114/
https://www.ncbi.nlm.nih.gov/pubmed/22952988
http://dx.doi.org/10.1371/journal.pone.0044518