Differential Proteomics and Functional Research following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis

Leber congenital amaurosis (LCA) is one of the most severe forms of inherited retinal degeneration and can be caused by mutations in at least 15 different genes. To clarify the proteomic differences in LCA eyes, a cohort of retinal degeneration 12 (rd12) mice, an LCA2 model caused by a mutation in t...

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Detalles Bibliográficos
Autores principales: Zheng, Qinxiang, Ren, Yueping, Tzekov, Radouil, Zhang, Yuanping, Chen, Bo, Hou, Jiangping, Zhao, Chunhui, Zhu, Jiali, Zhang, Ying, Dai, Xufeng, Ma, Shan, Li, Jia, Pang, Jijing, Qu, Jia, Li, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432120/
https://www.ncbi.nlm.nih.gov/pubmed/22953002
http://dx.doi.org/10.1371/journal.pone.0044855

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