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Riluzole-Triggered GSH Synthesis via Activation of Glutamate Transporters to Antagonize Methylmercury-Induced Oxidative Stress in Rat Cerebral Cortex

Objective. This study was to evaluate the effect of riluzole on methylmercury- (MeHg-) induced oxidative stress, through promotion of glutathione (GSH) synthesis by activating of glutamate transporters (GluTs) in rat cerebral cortex. Methods. Eighty rats were randomly assigned to four groups, contro...

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Detalles Bibliográficos
Autores principales: Deng, Yu, Xu, Zhao-Fa, Liu, Wei, Xu, Bin, Yang, Hai-Bo, Wei, Yan-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432391/
https://www.ncbi.nlm.nih.gov/pubmed/22966415
http://dx.doi.org/10.1155/2012/534705