Cargando…
Riluzole-Triggered GSH Synthesis via Activation of Glutamate Transporters to Antagonize Methylmercury-Induced Oxidative Stress in Rat Cerebral Cortex
Objective. This study was to evaluate the effect of riluzole on methylmercury- (MeHg-) induced oxidative stress, through promotion of glutathione (GSH) synthesis by activating of glutamate transporters (GluTs) in rat cerebral cortex. Methods. Eighty rats were randomly assigned to four groups, contro...
Autores principales: | Deng, Yu, Xu, Zhao-Fa, Liu, Wei, Xu, Bin, Yang, Hai-Bo, Wei, Yan-Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432391/ https://www.ncbi.nlm.nih.gov/pubmed/22966415 http://dx.doi.org/10.1155/2012/534705 |
Ejemplares similares
-
Functional re-evaluation of the putative glutathione transporters, RcGshT and RsGshT.
por: Li, L., et al.
Publicado: (1997) -
Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation
por: Xu, Yang, et al.
Publicado: (2022) -
Evaluation of the sodium-glutamate blocker riluzole in a preclinical model of ervical spinal cord injury
por: Wu, Yongchao, et al.
Publicado: (2010) -
An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists
por: Citraro, Rita, et al.
Publicado: (2023) -
Implication of the glutamate–cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis
por: Fournier, M., et al.
Publicado: (2017)