Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma

Sox2 (sex-determining region Y-Box) is one of the master transcriptional factors that are important in maintaining the pluripotency of embryonic stem cells (ESCs). In line with this function, Sox2 expression is largely restricted to ESCs and somatic stem cells. We report that Sox2 is expressed in ce...

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Detalles Bibliográficos
Autores principales: Gelebart, P, Hegazy, S A, Wang, P, Bone, K M, Anand, M, Sharon, D, Hitt, M, Pearson, J D, Ingham, R J, Ma, Y, Lai, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432482/
https://www.ncbi.nlm.nih.gov/pubmed/22885405
http://dx.doi.org/10.1038/bcj.2012.27

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