Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well As Activity of Xanthine Oxidase

Cytochrome P450 NADPH-reductase (P450R), inducible synthase (iNOS) and xanthine oxidase play an important role in the antracycline-related cardiotoxicity. The expression of P450R and iNOS is regulated by triiodothyronine. The aim of this study was to evaluate the effect of methimazole-induced hypoth...

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Detalles Bibliográficos
Autores principales: Dudka, Jaroslaw, Burdan, Franciszek, Korga, Agnieszka, Iwan, Magdalena, Madej-Czerwonka, Barbara, Cendrowska-Pinkosz, Monika, Korobowicz-Markiewicz, Agnieszka, Jodlowska-Jedrych, Barbara, Matysiak, Wlodzimierz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432562/
https://www.ncbi.nlm.nih.gov/pubmed/22966413
http://dx.doi.org/10.1155/2012/139327

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