Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence

BACKGROUND: HS-1-associated protein X-1 (Hax-1), is a multifunctional protein that has sequence homology to Bcl-2 family members. HAX-1 knockout animals reveal that it plays an essential protective role in the central nervous system against various stresses. Homozygous mutations in the HAX-1 gene ar...

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Detalles Bibliográficos
Autores principales: Li, Bin, Hu, Qingsong, Xu, Ranjie, Ren, Haigang, Fei, Erkang, Chen, Dong, Wang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432607/
https://www.ncbi.nlm.nih.gov/pubmed/22827267
http://dx.doi.org/10.1186/1471-2121-13-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432607/
https://www.ncbi.nlm.nih.gov/pubmed/22827267
http://dx.doi.org/10.1186/1471-2121-13-20

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