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Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence
BACKGROUND: HS-1-associated protein X-1 (Hax-1), is a multifunctional protein that has sequence homology to Bcl-2 family members. HAX-1 knockout animals reveal that it plays an essential protective role in the central nervous system against various stresses. Homozygous mutations in the HAX-1 gene ar...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432607/ https://www.ncbi.nlm.nih.gov/pubmed/22827267 http://dx.doi.org/10.1186/1471-2121-13-20 |