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Mouse ooplasm confers context-specific reprogramming capacity

Enucleated oocytes have the remarkable ability to reprogram somatic nuclei back to totipotency. Here we investigate genome-scale DNA methylation patterns after nuclear transfer and compare them to the dynamics at fertilization. We identify specific targets for DNA demethylation after nuclear transfe...

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Detalles Bibliográficos
Autores principales:	Chan, Michelle M., Smith, Zachary D., Egli, Dieter, Regev, Aviv, Meissner, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432711/ https://www.ncbi.nlm.nih.gov/pubmed/22902786 http://dx.doi.org/10.1038/ng.2382

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