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Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression

The Chk2-mediated deoxyribonucleic acid (DNA) damage checkpoint pathway is important for mitochondrial DNA (mtDNA) maintenance. We show in this paper that mtDNA itself affects cell cycle progression. Saccharomyces cerevisiae rho(0) cells, which lack mtDNA, were defective in G1- to S-phase progressio...

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Detalles Bibliográficos
Autores principales:	Crider, David G., García-Rodríguez, Luis J., Srivastava, Pallavi, Peraza-Reyes, Leonardo, Upadhyaya, Krishna, Boldogh, Istvan R., Pon, Liza A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432762/ https://www.ncbi.nlm.nih.gov/pubmed/22927468 http://dx.doi.org/10.1083/jcb.201205193

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