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γ-Tubulin plays a key role in inactivating APC/C(Cdh1) at the G(1)–S boundary

A γ-tubulin mutation in Aspergillus nidulans, mipA-D159, causes failure of inactivation of the anaphase-promoting complex/cyclosome (APC/C) in interphase, resulting in failure of cyclin B (CB) accumulation and removal of nuclei from the cell cycle. We have investigated the role of CdhA, the A. nidul...

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Detalles Bibliográficos
Autores principales: Edgerton-Morgan, Heather, Oakley, Berl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432763/
https://www.ncbi.nlm.nih.gov/pubmed/22927465
http://dx.doi.org/10.1083/jcb.201203115