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Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis

Chromokinesins are microtubule plus end–directed motor proteins that bind to chromosome arms. In Xenopus egg cell-free extracts, Xkid and Xklp1 are essential for bipolar spindle formation but the functions of the human homologues, hKID (KIF22) and KIF4A, are poorly understood. By using RNAi-mediated...

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Detalles Bibliográficos
Autores principales:	Wandke, Cornelia, Barisic, Marin, Sigl, Reinhard, Rauch, Veronika, Wolf, Frank, Amaro, Ana C., Tan, Chia H., Pereira, Antonio J., Kutay, Ulrike, Maiato, Helder, Meraldi, Patrick, Geley, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432768/ https://www.ncbi.nlm.nih.gov/pubmed/22945934 http://dx.doi.org/10.1083/jcb.201110060

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