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Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration
Satellite cells (SCs) are stem cells that mediate skeletal muscle growth and regeneration. Here, we observe that adult quiescent SCs and their activated descendants expressed the homeodomain transcription factor Six1. Genetic disruption of Six1 specifically in adult SCs impaired myogenic cell differ...
Autores principales: | Le Grand, Fabien, Grifone, Raphaëlle, Mourikis, Philippos, Houbron, Christophe, Gigaud, Carine, Pujol, Julien, Maillet, Marjorie, Pagès, Gilles, Rudnicki, Michael, Tajbakhsh, Shahragim, Maire, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432771/ https://www.ncbi.nlm.nih.gov/pubmed/22945933 http://dx.doi.org/10.1083/jcb.201201050 |
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