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Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials
Bioresorbable scaffolds (BRS) represent a novel approach in coronary stent technology. In contrast to the metallic stents, they provide transient scaffolding, thereby safeguarding early vessel patency and acute gain. Subsequently a process of “decomposition” occurs, that results in the complete abso...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Current Science Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432788/ https://www.ncbi.nlm.nih.gov/pubmed/22810889 http://dx.doi.org/10.1007/s11886-012-0295-5 |
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author | Bourantas, Christos V. Zhang, Yaojun Farooq, Vasim Garcia-Garcia, Hector M. Onuma, Yoshinobu Serruys, Patrick W. |
author_facet | Bourantas, Christos V. Zhang, Yaojun Farooq, Vasim Garcia-Garcia, Hector M. Onuma, Yoshinobu Serruys, Patrick W. |
author_sort | Bourantas, Christos V. |
collection | PubMed |
description | Bioresorbable scaffolds (BRS) represent a novel approach in coronary stent technology. In contrast to the metallic stents, they provide transient scaffolding, thereby safeguarding early vessel patency and acute gain. Subsequently a process of “decomposition” occurs, that results in the complete absorption of the scaffold. This reduces the risk of late complications, allowing the vessel to maintain its integrity and physiological function. This unique ability has attracted interest and nowadays several BRS are available. The aim of this review article is to describe the advances in the field, present the evidence from the preclinical and clinical evaluation of these devices, and provide an overview of the ongoing clinical trials that were designed to examine the effectiveness of BRS in the clinical setting. |
format | Online Article Text |
id | pubmed-3432788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Current Science Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-34327882012-09-07 Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials Bourantas, Christos V. Zhang, Yaojun Farooq, Vasim Garcia-Garcia, Hector M. Onuma, Yoshinobu Serruys, Patrick W. Curr Cardiol Rep Interventional Cardiology (DJ Moliterno, Section Editor) Bioresorbable scaffolds (BRS) represent a novel approach in coronary stent technology. In contrast to the metallic stents, they provide transient scaffolding, thereby safeguarding early vessel patency and acute gain. Subsequently a process of “decomposition” occurs, that results in the complete absorption of the scaffold. This reduces the risk of late complications, allowing the vessel to maintain its integrity and physiological function. This unique ability has attracted interest and nowadays several BRS are available. The aim of this review article is to describe the advances in the field, present the evidence from the preclinical and clinical evaluation of these devices, and provide an overview of the ongoing clinical trials that were designed to examine the effectiveness of BRS in the clinical setting. Current Science Inc. 2012-07-19 2012 /pmc/articles/PMC3432788/ /pubmed/22810889 http://dx.doi.org/10.1007/s11886-012-0295-5 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Interventional Cardiology (DJ Moliterno, Section Editor) Bourantas, Christos V. Zhang, Yaojun Farooq, Vasim Garcia-Garcia, Hector M. Onuma, Yoshinobu Serruys, Patrick W. Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title | Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title_full | Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title_fullStr | Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title_full_unstemmed | Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title_short | Bioresorbable Scaffolds: Current Evidence and Ongoing Clinical Trials |
title_sort | bioresorbable scaffolds: current evidence and ongoing clinical trials |
topic | Interventional Cardiology (DJ Moliterno, Section Editor) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432788/ https://www.ncbi.nlm.nih.gov/pubmed/22810889 http://dx.doi.org/10.1007/s11886-012-0295-5 |
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