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Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling

Chronic gastric inflammation developing after Helicobacter pylori (H. pylori) infection is responsible for either dyspeptic symptom relevant to gastritis/peptic ulcer or gastric tumorigenesis, in which acid suppressants, especially proton pump inhibitors (PPIs), play role in relieving dyspepsia as w...

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Detalles Bibliográficos
Autores principales: Lee, Jeong-Sang, Cho, Ji-Yoon, Song, Heup, Kim, Eun-Hee, Hahm, Ki-Baik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432830/
https://www.ncbi.nlm.nih.gov/pubmed/22962522
http://dx.doi.org/10.3164/jcbn.11-94