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TNF receptor family signaling in the development and functions of medullary thymic epithelial cells
Thymic epithelial cells (TECs) provide the microenvironment required for the development of T cells in the thymus. A unique property of medullary thymic epithelial cells (mTECs) is their expression of a wide range of tissue-restricted self-antigens, critically regulated by the nuclear protein AIRE,...
Autores principales: | Akiyama, Taishin, Shinzawa, Miho, Akiyama, Nobuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432834/ https://www.ncbi.nlm.nih.gov/pubmed/22969770 http://dx.doi.org/10.3389/fimmu.2012.00278 |
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