The role of hypoxic-inducible factor (HIF1α) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients

OBJECTIVES: Hypoxia-inducible factor (HIF1α) plays an integral role in response to hypoxia, controlling dozens of target genes including aldolaseC (ALDC), an important enzyme in the glycolytic pathway. It also induces angiogenesis, allowing survival and proliferation of cancer cells. The aims of our...

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Detalles Bibliográficos
Autores principales: Mhawech-Fauceglia, Paulette, Wang, Dan, Samrao, Damanzoopinder, Menesses, Teodulo, Godoy, Heidi, Ough, Faith, Lele, Shashikant, Liu, Song, Pejovic, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432840/
https://www.ncbi.nlm.nih.gov/pubmed/22923632
http://dx.doi.org/10.1136/bmjopen-2012-001450

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