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Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress

BACKGROUND: The expression of pro-angiogenic cytokines, such as vascular endothelial growth factor (VEGF) and interleukin-8/CXCL8 (IL-8), plays an important role in tumor growth and metastasis. Low oxygen tension within poorly-vascularized tumors is thought to be the prime stimulus causing the secre...

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Detalles Bibliográficos
Autores principales: Marjon, Philip L, Bobrovnikova-Marjon, Ekaterina V, Abcouwer, Steve F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC343294/
https://www.ncbi.nlm.nih.gov/pubmed/14738568
http://dx.doi.org/10.1186/1476-4598-3-4

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