Primary Small Cell Neuroendocrine Carcinoma of the Endometrium

BACKGROUND: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. CASE STUDY: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the...

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Autores principales: Abaid, Lisa N., Cupp, John S., Brown, John V., Goldstein, Bram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published online: August, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433003/
https://www.ncbi.nlm.nih.gov/pubmed/22949907
http://dx.doi.org/10.1159/000342006
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author Abaid, Lisa N.
Cupp, John S.
Brown, John V.
Goldstein, Bram H.
author_facet Abaid, Lisa N.
Cupp, John S.
Brown, John V.
Goldstein, Bram H.
author_sort Abaid, Lisa N.
collection PubMed
description BACKGROUND: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. CASE STUDY: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was negative for CD3 and CD20. Prior to chemotherapy, a completion lymphadenectomy was indicated to determine the presence of nodal metastases. CONCLUSION: The prognosis of small cell neuroendocrine carcinoma of the endometrium is unfavorable but prompt detection with surgery and adjuvant therapy may confer a better clinical outcome.
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spelling pubmed-34330032012-09-04 Primary Small Cell Neuroendocrine Carcinoma of the Endometrium Abaid, Lisa N. Cupp, John S. Brown, John V. Goldstein, Bram H. Case Rep Oncol Published online: August, 2012 BACKGROUND: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. CASE STUDY: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was negative for CD3 and CD20. Prior to chemotherapy, a completion lymphadenectomy was indicated to determine the presence of nodal metastases. CONCLUSION: The prognosis of small cell neuroendocrine carcinoma of the endometrium is unfavorable but prompt detection with surgery and adjuvant therapy may confer a better clinical outcome. S. Karger AG 2012-08-09 /pmc/articles/PMC3433003/ /pubmed/22949907 http://dx.doi.org/10.1159/000342006 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: August, 2012
Abaid, Lisa N.
Cupp, John S.
Brown, John V.
Goldstein, Bram H.
Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title_full Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title_fullStr Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title_full_unstemmed Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title_short Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
title_sort primary small cell neuroendocrine carcinoma of the endometrium
topic Published online: August, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433003/
https://www.ncbi.nlm.nih.gov/pubmed/22949907
http://dx.doi.org/10.1159/000342006
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