Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models

BACKGROUND: The tumor microenvironment contains a vast array of pro- and anti-inflammatory cytokines that alter myelopoiesis and lead to the maturation of immunosuppressive cells known as myeloid-derived suppressor cells (MDSCs). Incubating bone marrow (BM) precursors with a combination of granulocy...

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Detalles Bibliográficos
Autores principales: Hammami, Ines, Chen, Jingkui, Murschel, Frederic, Bronte, Vincenzo, De Crescenzo, Gregory, Jolicoeur, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433355/
https://www.ncbi.nlm.nih.gov/pubmed/22762146
http://dx.doi.org/10.1186/1471-2121-13-18

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