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Gene regulatory network modeling via global optimization of high-order dynamic Bayesian network

BACKGROUND: Dynamic Bayesian network (DBN) is among the mainstream approaches for modeling various biological networks, including the gene regulatory network (GRN). Most current methods for learning DBN employ either local search such as hill-climbing, or a meta stochastic global optimization framew...

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Detalles Bibliográficos
Autores principales: Xuan, Nguyen, Chetty, Madhu, Coppel, Ross, Wangikar, Pramod P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433362/
https://www.ncbi.nlm.nih.gov/pubmed/22694481
http://dx.doi.org/10.1186/1471-2105-13-131