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Menin and p53 have non-synergistic effects on tumorigenesis in mice
BACKGROUND: While it is now more than a decade since the first description of the gene mutation underlying the tumour predisposition syndrome multiple endocrine neoplasia type 1 (MEN1), the mechanism by which its protein product menin acts to prevent development of tumours is still poorly understood...
Autores principales: | Loffler, Kelly A, Mould, Arne W, Waring, Paul M, Hayward, Nicholas K, Kay, Graham F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433377/ https://www.ncbi.nlm.nih.gov/pubmed/22708734 http://dx.doi.org/10.1186/1471-2407-12-252 |
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