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Menin and p53 have non-synergistic effects on tumorigenesis in mice

BACKGROUND: While it is now more than a decade since the first description of the gene mutation underlying the tumour predisposition syndrome multiple endocrine neoplasia type 1 (MEN1), the mechanism by which its protein product menin acts to prevent development of tumours is still poorly understood...

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Detalles Bibliográficos
Autores principales: Loffler, Kelly A, Mould, Arne W, Waring, Paul M, Hayward, Nicholas K, Kay, Graham F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433377/
https://www.ncbi.nlm.nih.gov/pubmed/22708734
http://dx.doi.org/10.1186/1471-2407-12-252

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