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Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-Activated Receptor Alpha Network

Recent data suggest that the etiology of several metabolic diseases is closely associated with transcriptome alteration by aberrant histone methylation. We performed DNA microarray and ChIP-on-chip analyses to examine transcriptome profiling and trimethylation alterations to identify the genomic sig...

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Detalles Bibliográficos
Autores principales: Jun, Hee-Jin, Kim, Jinyoung, Hoang, Minh-Hien, Lee, Sung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433434/
https://www.ncbi.nlm.nih.gov/pubmed/22973438
http://dx.doi.org/10.1371/journal.pone.0044345