Ribavirin Enhances the Action of Interferon-α against Hepatitis C Virus by Promoting the p53 Activity through the ERK1/2 Pathway

BACKGROUND/AIMS: Ribavirin significantly enhances the antiviral response of interferon-α (IFN-α) against Hepatitis C virus (HCV), but the underlying mechanisms remain poorly understood. Recently, p53 has been identified as an important factor involving the suppression of HCV replication in hepatocyt...

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Detalles Bibliográficos
Autores principales: Liu, Wei-Liang, Yang, Hung-Chih, Su, Wen-Cheng, Wang, Chih-Chiang, Chen, Hui-Ling, Wang, Hurng-Yi, Huang, Wen-Hung, Chen, Ding-Shinn, Lai, Ming-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433463/
https://www.ncbi.nlm.nih.gov/pubmed/22962590
http://dx.doi.org/10.1371/journal.pone.0043824

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