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Calcium Input Frequency, Duration and Amplitude Differentially Modulate the Relative Activation of Calcineurin and CaMKII

NMDA receptor dependent long-term potentiation (LTP) and long-term depression (LTD) are two prominent forms of synaptic plasticity, both of which are triggered by post-synaptic calcium elevation. To understand how calcium selectively stimulates two opposing processes, we developed a detailed computa...

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Detalles Bibliográficos
Autores principales: Li, Lu, Stefan, Melanie I., Le Novère, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433481/
https://www.ncbi.nlm.nih.gov/pubmed/22962589
http://dx.doi.org/10.1371/journal.pone.0043810