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Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

The major heat shock protein Hsp72 is expressed at elevated levels in many human cancers and its expression correlates with tumor progression. Here we investigated the role of Hsp72 in Her2 oncogene-induced neoplastic transformation and tumorigenesis. Expression of Her2 in untransformed MCF10A mamma...

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Detalles Bibliográficos
Autores principales: Meng, Le, Hunt, Clayton, Yaglom, Julia A., Gabai, Vladimir L., Sherman, Michael Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433756/
https://www.ncbi.nlm.nih.gov/pubmed/21297664
http://dx.doi.org/10.1038/onc.2011.5