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T Cell Activation Markers and African Mitochondrial DNA Haplogroups among Non-Hispanic Black Participants in AIDS Clinical Trials Group Study 384

INTRODUCTION: Mitochondrial function influences T cell dynamics and is affected by mitochondrial DNA (mtDNA) variation. We previously reported an association between African mtDNA haplogroup L2 and less robust CD4 cell recovery on antiretroviral therapy (ART) in non-Hispanic black ACTG 384 subjects....

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Detalles Bibliográficos
Autores principales: Hulgan, Todd, Robbins, Gregory K., Kalams, Spyros A., Samuels, David C., Grady, Benjamin, Shafer, Robert, Murdock, Deborah G., Selph, Doug, Haas, David W., Pollard, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433792/
https://www.ncbi.nlm.nih.gov/pubmed/22970105
http://dx.doi.org/10.1371/journal.pone.0043803