Multi High-Throughput Approach for Highly Selective Identification of Vaccine Candidates: the Group A Streptococcus Case

We propose an experimental strategy for highly accurate selection of candidates for bacterial vaccines without using in vitro and/or in vivo protection assays. Starting from the observation that efficacious vaccines are constituted by conserved, surface-associated and/or secreted components, the str...

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Detalles Bibliográficos
Autores principales: Bensi, Giuliano, Mora, Marirosa, Tuscano, Giovanna, Biagini, Massimiliano, Chiarot, Emiliano, Bombaci, Mauro, Capo, Sabrina, Falugi, Fabiana, Manetti, Andrea G. O., Donato, Paolo, Swennen, Erwin, Gallotta, Marilena, Garibaldi, Manuela, Pinto, Vittoria, Chiappini, Nico, Musser, James M., Janulczyk, Robert, Mariani, Massimo, Scarselli, Maria, Telford, John L., Grifantini, Renata, Norais, Nathalie, Margarit, Immaculada, Grandi, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433891/
https://www.ncbi.nlm.nih.gov/pubmed/22286755
http://dx.doi.org/10.1074/mcp.M111.015693

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