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Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009

BACKGROUND: Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia. METHODS: Between 1(st) January 2009 t...

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Autores principales: Chew, Boon How, Mastura, Ismail, Shariff-Ghazali, Sazlina, Lee, Ping Yein, Cheong, Ai Theng, Ahmad, Zaiton, Taher, Sri Wahyu, Haniff, Jamaiyah, Mustapha, Feisul Idzwan, Bujang, Mohd Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434063/
https://www.ncbi.nlm.nih.gov/pubmed/22607105
http://dx.doi.org/10.1186/1475-2840-11-54
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author Chew, Boon How
Mastura, Ismail
Shariff-Ghazali, Sazlina
Lee, Ping Yein
Cheong, Ai Theng
Ahmad, Zaiton
Taher, Sri Wahyu
Haniff, Jamaiyah
Mustapha, Feisul Idzwan
Bujang, Mohd Adam
author_facet Chew, Boon How
Mastura, Ismail
Shariff-Ghazali, Sazlina
Lee, Ping Yein
Cheong, Ai Theng
Ahmad, Zaiton
Taher, Sri Wahyu
Haniff, Jamaiyah
Mustapha, Feisul Idzwan
Bujang, Mohd Adam
author_sort Chew, Boon How
collection PubMed
description BACKGROUND: Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia. METHODS: Between 1(st) January 2009 to 31(st) December 2009, data from 70 889 patients with Type 2 diabetes was obtained from the Adult Diabetes Control and Management Registry for analysis; 303 centers participated in the study. Their demographic characteristics, the nature of their diabetes, their state of hypertension, treatment modalities, risk factors, and complications are described. Based on their most recent BP values, subjects were divided into controlled BP and uncontrolled BP and their clinical determinants compared. Independent determinants were identified using multivariate logistic regression. RESULTS: The mean age of patients at diagnosis of diabetes was 52.3 ± 11.1 years old. Most were women (59.0 %) and of Malay ethnicity (61.9 %). The mean duration of diabetes was 5.9 ± 5.6 years. A total of 57.4 % were hypertensive. Of the 56 503 blood pressure (BP) measured, 13 280 (23.5 %) patients had BP <130/80 mmHg. Eighteen percent was on > two anti-hypertensive agents. Health clinics without doctor, older age (≥ 50 years old), shorter duration of diabetes (< 5 years), Malay, overweight were determinants for uncontrolled blood pressure (BP ≥130/80 mmHg). Patients who were on anti-hypertensive agent/s were 2.7 times more likely to have BP ≥130/80 mmHg. Type 2 diabetes patients who had ischaemic heart disease or nephropathy were about 20 % and 15 % more likely to have their blood pressure treated to target respectively. CONCLUSIONS: Major independent determinants of uncontrolled BP in our group of T2D patients were Malay ethnicity, older age, recent diagnosis of diabetes, overweight and follow-up at health clinics without a doctor and possibly the improper use of anti hypertensive agent. More effort, education and resources, especially in the primary health care centres are needed to improve hypertensive care among our patients with diabetes.
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spelling pubmed-34340632012-09-06 Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009 Chew, Boon How Mastura, Ismail Shariff-Ghazali, Sazlina Lee, Ping Yein Cheong, Ai Theng Ahmad, Zaiton Taher, Sri Wahyu Haniff, Jamaiyah Mustapha, Feisul Idzwan Bujang, Mohd Adam Cardiovasc Diabetol Original Investigation BACKGROUND: Uncontrolled blood pressure (BP) is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D) patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia. METHODS: Between 1(st) January 2009 to 31(st) December 2009, data from 70 889 patients with Type 2 diabetes was obtained from the Adult Diabetes Control and Management Registry for analysis; 303 centers participated in the study. Their demographic characteristics, the nature of their diabetes, their state of hypertension, treatment modalities, risk factors, and complications are described. Based on their most recent BP values, subjects were divided into controlled BP and uncontrolled BP and their clinical determinants compared. Independent determinants were identified using multivariate logistic regression. RESULTS: The mean age of patients at diagnosis of diabetes was 52.3 ± 11.1 years old. Most were women (59.0 %) and of Malay ethnicity (61.9 %). The mean duration of diabetes was 5.9 ± 5.6 years. A total of 57.4 % were hypertensive. Of the 56 503 blood pressure (BP) measured, 13 280 (23.5 %) patients had BP <130/80 mmHg. Eighteen percent was on > two anti-hypertensive agents. Health clinics without doctor, older age (≥ 50 years old), shorter duration of diabetes (< 5 years), Malay, overweight were determinants for uncontrolled blood pressure (BP ≥130/80 mmHg). Patients who were on anti-hypertensive agent/s were 2.7 times more likely to have BP ≥130/80 mmHg. Type 2 diabetes patients who had ischaemic heart disease or nephropathy were about 20 % and 15 % more likely to have their blood pressure treated to target respectively. CONCLUSIONS: Major independent determinants of uncontrolled BP in our group of T2D patients were Malay ethnicity, older age, recent diagnosis of diabetes, overweight and follow-up at health clinics without a doctor and possibly the improper use of anti hypertensive agent. More effort, education and resources, especially in the primary health care centres are needed to improve hypertensive care among our patients with diabetes. BioMed Central 2012-05-18 /pmc/articles/PMC3434063/ /pubmed/22607105 http://dx.doi.org/10.1186/1475-2840-11-54 Text en Copyright ©2012 Chew et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Investigation
Chew, Boon How
Mastura, Ismail
Shariff-Ghazali, Sazlina
Lee, Ping Yein
Cheong, Ai Theng
Ahmad, Zaiton
Taher, Sri Wahyu
Haniff, Jamaiyah
Mustapha, Feisul Idzwan
Bujang, Mohd Adam
Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_full Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_fullStr Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_full_unstemmed Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_short Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009
title_sort determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the malaysian diabetes registry 2009
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434063/
https://www.ncbi.nlm.nih.gov/pubmed/22607105
http://dx.doi.org/10.1186/1475-2840-11-54
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