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Probing the activation sequence of NMDA receptors with lurcher mutations

N-methyl-d-aspartate (NMDA) receptor activation involves a dynamic series of structural rearrangements initiated by glutamate binding to glycine-loaded receptors and culminates with the clearing of the permeation pathway, which allows ionic flux. Along this sequence, three rate-limiting transitions...

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Detalles Bibliográficos
Autores principales:	Murthy, Swetha E., Shogan, Tamer, Page, Jessica C., Kasperek, Eileen M., Popescu, Gabriela K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434102/ https://www.ncbi.nlm.nih.gov/pubmed/22891278 http://dx.doi.org/10.1085/jgp.201210786

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