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Knocking Down Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) Reverts Chemoresistance through Inactivation of Src and Bcr-Abl Proteins

The development of multidrug resistance (MDR) limits the efficacy of continuous chemotherapeutic treatment in chronic myelogenous leukemia (CML). Low molecular weight protein tyrosine phosphatase (LMW-PTP) is up-regulated in several cancers and has been associated to poor prognosis. This prompted us...

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Detalles Bibliográficos
Autores principales:	Ferreira, Paula A., Ruela-de-Sousa, Roberta R., Queiroz, Karla C. S., Souza, Ana Carolina S., Milani, Renato, Pilli, Ronaldo Aloise, Peppelenbosch, Maikel P., den Hertog, Jeroen, Ferreira, Carmen V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434132/ https://www.ncbi.nlm.nih.gov/pubmed/22957062 http://dx.doi.org/10.1371/journal.pone.0044312

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