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Corticotropin-Releasing Hormone Receptor 1 Gene Variants in Irritable Bowel Syndrome

BACKGROUND: Corticotropin-releasing hormone (CRH) acts mainly via the CRH receptor 1 (CRH-R1) and plays a crucial role in the stress-induced pathophysiology of irritable bowel syndrome (IBS). Several studies have demonstrated that variants of the CRH-R1 gene carry a potential risk for depression, bu...

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Detalles Bibliográficos
Autores principales:	Sato, Naoko, Suzuki, Naoki, Sasaki, Ayaka, Aizawa, Emiko, Obayashi, Takeshi, Kanazawa, Motoyori, Mizuno, Tomoko, Kano, Michiko, Aoki, Masashi, Fukudo, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434156/ https://www.ncbi.nlm.nih.gov/pubmed/22957021 http://dx.doi.org/10.1371/journal.pone.0042450

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