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Secreted Protein Acidic and Rich in Cysteine (SPARC) Suppresses Angiogenesis by Down-Regulating the Expression of VEGF and MMP-7 in Gastric Cancer

BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein that functions to inhibit angiogenesis, proliferation, and invasion in different types of cancer. The ability of SPARC to modulate neovascularisation is believed to be mediated in part by its ability to modulate the e...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-Ling, Chen, Guo-Wei, Liu, Yu-Cun, Wang, Peng-Yuan, Wang, Xin, Wan, Yuan-Lian, Zhu, Jing, Gao, Hong-Qiao, Yin, Jie, Wang, Wei, Tian, Mao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434168/
https://www.ncbi.nlm.nih.gov/pubmed/22957090
http://dx.doi.org/10.1371/journal.pone.0044618