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Secreted Protein Acidic and Rich in Cysteine (SPARC) Suppresses Angiogenesis by Down-Regulating the Expression of VEGF and MMP-7 in Gastric Cancer
BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein that functions to inhibit angiogenesis, proliferation, and invasion in different types of cancer. The ability of SPARC to modulate neovascularisation is believed to be mediated in part by its ability to modulate the e...
Autores principales: | Zhang, Jun-Ling, Chen, Guo-Wei, Liu, Yu-Cun, Wang, Peng-Yuan, Wang, Xin, Wan, Yuan-Lian, Zhu, Jing, Gao, Hong-Qiao, Yin, Jie, Wang, Wei, Tian, Mao-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434168/ https://www.ncbi.nlm.nih.gov/pubmed/22957090 http://dx.doi.org/10.1371/journal.pone.0044618 |
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