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An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer Drugs

The epidermal growth factor receptor (EGFR) is a well-established target for cancer treatment. EGFR tyrosine kinase (TK) inhibitors, such as gefinitib and erlotinib, have been developed as anti-cancer drugs. Although non-small cell lung carcinoma with an activating EGFR mutation, L858R, responds wel...

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Detalles Bibliográficos
Autores principales:	Bae, Young-Ki, Sung, Jee Young, Kim, Yong-Nyun, Kim, Sunshin, Hong, Kyeong Man, Kim, Heung Tae, Choi, Min Sung, Kwon, Jae Young, Shim, Jaegal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434183/ https://www.ncbi.nlm.nih.gov/pubmed/22957020 http://dx.doi.org/10.1371/journal.pone.0042441

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