Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...

Descripción completa

Detalles Bibliográficos
Autores principales: Beheshti Zavareh, Reza, Sukhai, Mahadeo A., Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Simpson, Craig D., Maclean, Neil, Zih, Francis, Ketela, Troy, Swallow, Carol J., Moffat, Jason, Rose, David R., Schachter, Harry, Schimmer, Aaron D., Dennis, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434202/
https://www.ncbi.nlm.nih.gov/pubmed/22957033
http://dx.doi.org/10.1371/journal.pone.0043721

Ejemplares similares

Ejemplares similares