Cargando…

Computational Studies on the Substrate Interactions of Influenza A Virus PB2 Subunit

Influenza virus, which spreads around the world in seasonal epidemics and leads to large numbers of deaths every year, has several ribonucleoproteins in the central core of the viral particle. These viral ribonucleoproteins can specifically bind the conserved 3′ and 5′ caps of the viral RNAs with re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ya-Jun, Wang, Jing-Fang, Ping, Jie, Yu, Yao, Wang, Ying, Lian, Peng, Li, Xuan, Li, Yi-Xue, Hao, Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434214/ https://www.ncbi.nlm.nih.gov/pubmed/22957044 http://dx.doi.org/10.1371/journal.pone.0044079

Ejemplares similares

In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery
por: Huang, Daniel Tsung-Ning, et al.
Publicado: (2017)

The Host-Dependent Interaction of α-Importins with Influenza PB2 Polymerase Subunit Is Required for Virus RNA Replication
por: Resa-Infante, Patricia, et al.
Publicado: (2008)

Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein
por: Ling, Yue-Huan, et al.
Publicado: (2022)

Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A
por: Camacho-Zarco, Aldo R., et al.
Publicado: (2020)

The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix
por: Long, Joshua C. D., et al.
Publicado: (2016)

Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins
por: Zhang, Xiaohan, et al.
Publicado: (2020)

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus
por: Gabriel, Gülsah, et al.
Publicado: (2008)

Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA(2) subunit
por: Xu, Wang, et al.
Publicado: (2022)

Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit
por: Ma, Xiaolei, et al.
Publicado: (2017)

Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit
por: Chan, Johnson Jor-Shing, et al.
Publicado: (2023)

The C-Terminal Domains of the PB2 Subunit of the Influenza A Virus RNA Polymerase Directly Interact with Cellular GTPase Rab11a
por: Veler, Hana, et al.
Publicado: (2022)

Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein
por: Li, Chunfeng, et al.
Publicado: (2014)

KAP1 Positively Modulates Influenza A Virus Replication by Interacting with PB2 and NS1 Proteins in Human Lung Epithelial Cells
por: Feng, Huapeng, et al.
Publicado: (2022)

Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism
por: Ping, Jie, et al.
Publicado: (2013)

A Novel Functional Site in the PB2 Subunit of Influenza A Virus Essential for Acetyl-CoA Interaction, RNA Polymerase Activity, and Viral Replication
por: Hatakeyama, Dai, et al.
Publicado: (2014)

Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates
por: Sandu, Cristinel, et al.
Publicado: (2015)

TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase
por: Fu, Bishi, et al.
Publicado: (2015)

PB1F2 from Influenza A Virus Regulates the Interaction between Cytochrome C and Cardiolipin
por: Wang, Yujuan, et al.
Publicado: (2022)

The PA Subunit of the Influenza Virus Polymerase Complex Affects Replication and Airborne Transmission of the H9N2 Subtype Avian Influenza Virus
por: Hao, Mengchan, et al.
Publicado: (2019)

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
por: Armour, Brianna L., et al.
Publicado: (2013)

Preclinical Study of ZSP1273, a Potent Antiviral Inhibitor of Cap Binding to the PB2 Subunit of Influenza A Polymerase
por: Chen, Xiaoxin, et al.
Publicado: (2023)

PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence
por: Wang, Guangwen, et al.
Publicado: (2022)

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
por: Tarendeau, Franck, et al.
Publicado: (2008)

The chloroplast ribosomal protein large subunit 1 interacts with viral polymerase and promotes virus infection
por: Cheng, De-Jie, et al.
Publicado: (2021)

Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery
por: Chang, Ting-Ya, et al.
Publicado: (2017)

Atlas on substrate recognition subunits of CRL2 E3 ligases
por: Wang, Siwei, et al.
Publicado: (2016)

Mutation E48K in PB1 Polymerase Subunit Improves Stability of a Candidate Live Attenuated Influenza B Virus Vaccine
por: Mo, Jongsuk, et al.
Publicado: (2021)

Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine
por: Nogales, Aitor, et al.
Publicado: (2022)

Structure-based drug discovery for combating influenza virus by targeting the PA–PB1 interaction
por: Watanabe, Ken, et al.
Publicado: (2017)

Amino acid sites related to the PB2 subunits of IDV affect polymerase activity
por: Wang, Yutian, et al.
Publicado: (2021)

Fabrication of subunit nanovaccines by physical interaction
por: Chen, HaoLin, et al.
Publicado: (2022)

Influenza A Virus PB1-F2 Gene in Recent Taiwanese Isolates
por: Chen, Guang-Wu, et al.
Publicado: (2004)

Interaction between influenza A virus nucleoprotein and PB2 cap-binding domain is mediated by RNA
por: Szeto, Wun-Chung, et al.
Publicado: (2020)

Functional Analysis of Conserved Motifs in Influenza Virus PB1 Protein
por: Chu, Caroline, et al.
Publicado: (2012)

Expulsion mechanism of the substrate-translocating subunit in ECF transporters
por: Thangaratnarajah, Chancievan, et al.
Publicado: (2023)

Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication
por: He, Jun, et al.
Publicado: (2022)

Construction of Multilevel Structure for Avian Influenza Virus System Based on Granular Computing
por: Li, Yang, et al.
Publicado: (2017)

Protein transduction domain-mediated influenza NP subunit vaccine generates a potent immune response and protection against influenza virus in mice
por: Yin, Yuan, et al.
Publicado: (2020)

Autophagy is involved in the replication of H9N2 influenza virus via the regulation of oxidative stress in alveolar epithelial cells
por: Zhang, Rui-hua, et al.
Publicado: (2021)

Safety and immunogenicity of an MF59™-adjuvanted subunit influenza vaccine in elderly Chinese subjects
por: Li, Rongcheng, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_hdisckp3fdlsn78h401g18fr0q