Dissecting DNA damage response pathways by analyzing protein localization and abundance changes during DNA replication stress

Re-localization of proteins is a hallmark of the DNA damage response. We use high-throughput microscopic screening of the yeast GFP fusion collection to develop a systems-level view of protein re-organization following drug-induced DNA replication stress. Changes in protein localization and abundanc...

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Detalles Bibliográficos
Autores principales: Tkach, Johnny M., Yimit, Askar, Lee, Anna Y., Riffle, Michael, Costanzo, Michael, Jaschob, Daniel, Hendry, Jason A., Ou, Jiongwen, Moffat, Jason, Boone, Charles, Davis, Trisha N., Nislow, Corey, Brown, Grant W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434236/
https://www.ncbi.nlm.nih.gov/pubmed/22842922
http://dx.doi.org/10.1038/ncb2549

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