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Migraine and Genetic Polymorphisms: An Overview
The relationship between genetic polymorphisms and migraine as a cause of an increased risk of thrombotic disorders development is still debated In this respect, factor V Leiden, factor V (H1299R), prothrombin G20210A, factor XIII (V34L), β-fibrinogen, MTHFR (C677T), MTHFR (A1298C), APO E, PAI-1, HP...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434423/ https://www.ncbi.nlm.nih.gov/pubmed/22962564 http://dx.doi.org/10.2174/1874205X01206010065 |
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author | Pizza, Vincenzo Agresta, Anella Agresta, Antonio Lamaida, Eros Lamaida, Norman Infante, Francesco Capasso, Anna |
author_facet | Pizza, Vincenzo Agresta, Anella Agresta, Antonio Lamaida, Eros Lamaida, Norman Infante, Francesco Capasso, Anna |
author_sort | Pizza, Vincenzo |
collection | PubMed |
description | The relationship between genetic polymorphisms and migraine as a cause of an increased risk of thrombotic disorders development is still debated In this respect, factor V Leiden, factor V (H1299R), prothrombin G20210A, factor XIII (V34L), β-fibrinogen, MTHFR (C677T), MTHFR (A1298C), APO E, PAI-1, HPA-1 and ACE I/D seem to play a determinant role in vascular diseases related to migraine. The present review analyzes both the incidence of the above genetic vascular mutations in migraineurs and the most re-cent developments related to genetic polymorphisms and migraine. |
format | Online Article Text |
id | pubmed-3434423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-34344232012-09-07 Migraine and Genetic Polymorphisms: An Overview Pizza, Vincenzo Agresta, Anella Agresta, Antonio Lamaida, Eros Lamaida, Norman Infante, Francesco Capasso, Anna Open Neurol J Article The relationship between genetic polymorphisms and migraine as a cause of an increased risk of thrombotic disorders development is still debated In this respect, factor V Leiden, factor V (H1299R), prothrombin G20210A, factor XIII (V34L), β-fibrinogen, MTHFR (C677T), MTHFR (A1298C), APO E, PAI-1, HPA-1 and ACE I/D seem to play a determinant role in vascular diseases related to migraine. The present review analyzes both the incidence of the above genetic vascular mutations in migraineurs and the most re-cent developments related to genetic polymorphisms and migraine. Bentham Open 2012-08-17 /pmc/articles/PMC3434423/ /pubmed/22962564 http://dx.doi.org/10.2174/1874205X01206010065 Text en © Finsterer and Stöllberger; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Pizza, Vincenzo Agresta, Anella Agresta, Antonio Lamaida, Eros Lamaida, Norman Infante, Francesco Capasso, Anna Migraine and Genetic Polymorphisms: An Overview |
title | Migraine and Genetic Polymorphisms: An Overview |
title_full | Migraine and Genetic Polymorphisms: An Overview |
title_fullStr | Migraine and Genetic Polymorphisms: An Overview |
title_full_unstemmed | Migraine and Genetic Polymorphisms: An Overview |
title_short | Migraine and Genetic Polymorphisms: An Overview |
title_sort | migraine and genetic polymorphisms: an overview |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434423/ https://www.ncbi.nlm.nih.gov/pubmed/22962564 http://dx.doi.org/10.2174/1874205X01206010065 |
work_keys_str_mv | AT pizzavincenzo migraineandgeneticpolymorphismsanoverview AT agrestaanella migraineandgeneticpolymorphismsanoverview AT agrestaantonio migraineandgeneticpolymorphismsanoverview AT lamaidaeros migraineandgeneticpolymorphismsanoverview AT lamaidanorman migraineandgeneticpolymorphismsanoverview AT infantefrancesco migraineandgeneticpolymorphismsanoverview AT capassoanna migraineandgeneticpolymorphismsanoverview |