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Translesion DNA Polymerases and Cancer

DNA repair has been regarded as an important barrier to carcinogenesis. The newly discovered field of translesion synthesis (TLS) has made it apparent that mammalian cells need distinct polymerases to efficiently and accurately bypass DNA lesions. Perturbation of TLS polymerase activity by mutation,...

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Detalles Bibliográficos
Autores principales:	Makridakis, Nick M., Reichardt, Juergen K. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434439/ https://www.ncbi.nlm.nih.gov/pubmed/22973298 http://dx.doi.org/10.3389/fgene.2012.00174

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