Cargando…
Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis
Notch pathway is a well-known factor in the development of lymphoid lineage. However, its role in the myeloid lineage has remained ambiguous. We looked into the effect of Notch1 on the megakaryocytic lineage commitment and found an increase in megakaryocyte-specific lineage markers upon transfection...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434659/ https://www.ncbi.nlm.nih.gov/pubmed/22914328 http://dx.doi.org/10.1038/cddis.2012.119 |