Cargando…

PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation

Recent observations indicate prostatic diseases are comorbidities of systemic metabolic dysfunction. These discoveries revealed fundamental questions regarding the nature of prostate metabolism. We previously showed that prostate-specific ablation of PPARγ in mice resulted in tumorigenesis and activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strand, D W, Jiang, M, Murphy, T A, Yi, Y, Konvinse, K C, Franco, O E, Wang, Y, Young, J D, Hayward, S W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434663/ https://www.ncbi.nlm.nih.gov/pubmed/22874998 http://dx.doi.org/10.1038/cddis.2012.99

Ejemplares similares

Isoform-specific functions of PPARγ in gene regulation and metabolism
por: Hu, Wenxiang, et al.
Publicado: (2022)

Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy
por: Jiang, Ming, et al.
Publicado: (2009)

Role of PPARγ in the Differentiation and Function of Neurons
por: Quintanilla, Rodrigo A., et al.
Publicado: (2014)

PPARγ Regulates Trophoblast Proliferation and Promotes Labyrinthine Trilineage Differentiation
por: Parast, Mana M., et al.
Publicado: (2009)

Shockwaves Suppress Adipocyte Differentiation via Decrease in PPARγ
por: Cho, Wonkyoung, et al.
Publicado: (2020)

PPAR-γ Regulates Trophoblast Differentiation in the BeWo Cell Model
por: Levytska, Khrystyna, et al.
Publicado: (2014)

PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma
por: Chaffer, Christine L, et al.
Publicado: (2006)

A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2
por: Takenaka, Yasuhiro, et al.
Publicado: (2013)

Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?
por: Pap, Attila, et al.
Publicado: (2016)

Pathophysiological Roles of PPARγ in Gastrointestinal Epithelial Cells
por: Necela, Brian M., et al.
Publicado: (2008)

PPARγ Agonists Promote Oligodendrocyte Differentiation of Neural Stem Cells by Modulating Stemness and Differentiation Genes
por: Kanakasabai, Saravanan, et al.
Publicado: (2012)

PPARγ agonist through the terminal differentiation phase is essential for adipogenic differentiation of fetal ovine preadipocytes
por: Pu, Yong, et al.
Publicado: (2017)

Metformin promotes osteogenic differentiation and prevents hyperglycaemia-induced osteoporosis by suppressing PPARγ expression: Metformin prevents osteoporosis by suppressing PPARγ
por: Zheng, Lifeng, et al.
Publicado: (2023)

The role of PPARγ in prostate cancer development and progression
por: Hartley, Andrew, et al.
Publicado: (2022)

The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression
por: Won Park, Kye, et al.
Publicado: (2010)

Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism
por: Lizcano, Fernando, et al.
Publicado: (2013)

KLF13 promotes porcine adipocyte differentiation through PPARγ activation
por: Jiang, Shuzhong, et al.
Publicado: (2015)

Deciphering the interaction between Twist1 and PPARγ during adipocyte differentiation
por: Sun, Leilei, et al.
Publicado: (2023)

Akt isoforms differentially provide for chemoresistance in prostate cancer
por: Ma, Bo, et al.
Publicado: (2022)

Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms
por: Ross, Fiona A., et al.
Publicado: (2016)

PPAR-δ agonist affects adipo-chondrogenic differentiation of human mesenchymal stem cells through the expression of PPAR-γ
por: Kim, Dong Hyun, et al.
Publicado: (2020)

Peroxisome proliferator-activated receptor γ isoforms differentially regulate preadipocyte proliferation, apoptosis, and differentiation in chickens
por: Mu, Fang, et al.
Publicado: (2020)

Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ
por: Jin, Youngnam N., et al.
Publicado: (2012)

The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders
por: Porcuna, Jesús, et al.
Publicado: (2021)

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity
por: Basu-Roy, Upal, et al.
Publicado: (2016)

Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression
por: Xue, Peng, et al.
Publicado: (2019)

A transcriptomic study of myogenic differentiation under the overexpression of PPARγ by RNA-Seq
por: He, Kan, et al.
Publicado: (2017)

Differential Effects of Cancer-Associated Mutations Enriched in Helix H3 of PPARγ
por: Jang, Dong Man, et al.
Publicado: (2020)

The downstream PPARγ target LRRC1 participates in early stage adipocytic differentiation
por: Wang, Xinping, et al.
Publicado: (2022)

Differential Ligand Binding Affinities of Human Estrogen Receptor-α Isoforms
por: Lin, Amanda H. Y., et al.
Publicado: (2013)

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
por: Roberts, Lee D, et al.
Publicado: (2011)

The CD36-PPARγ Pathway in Metabolic Disorders
por: Maréchal, Loïze, et al.
Publicado: (2018)

Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo
por: Yang, Shu, et al.
Publicado: (2016)

Pparγ2 Is a Key Driver of Longevity in the Mouse
por: Argmann, Carmen, et al.
Publicado: (2009)

Characterization and Functional Assessment of Mouse PPARγ1 Promoter
por: Lachinani, Liana, et al.
Publicado: (2012)

PPARγ and Cognitive Performance
por: d’Angelo, Michele, et al.
Publicado: (2019)

Molecular Modeling of Allosteric Site of Isoform-Specific Inhibition of the Peroxisome Proliferator-Activated Receptor PPARγ
por: Almahmoud, Suliman, et al.
Publicado: (2022)

Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes
por: John, Elisabeth, et al.
Publicado: (2012)

Chlorogenic Acid Functions as a Novel Agonist of PPARγ2 during the Differentiation of Mouse 3T3-L1 Preadipocytes
por: Peng, Shu-guang, et al.
Publicado: (2018)

Expression of peroxisome proliferator-activated receptor (PPAR)γ in gastric cancer and inhibitory effects of PPARγ agonists
por: Sato, H, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_97vesq9gkerqucf1pfq64k5ihj