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An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity
Huntington's disease (HD) is a devastating neurodegenerative disorder whose main hallmark is brain atrophy. However, several peripheral organs are considerably affected and their symptoms may, in fact, manifest before those resulting from brain pathology. HD is of genetic origin and caused by a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434668/ https://www.ncbi.nlm.nih.gov/pubmed/22932724 http://dx.doi.org/10.1038/cddis.2012.121 |