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Met receptor tyrosine kinase signals through a cortactin–Gab1 scaffold complex, to mediate invadopodia
Invasive carcinoma cells form actin-rich matrix-degrading protrusions called invadopodia. These structures resemble podosomes produced by some normal cells and play a crucial role in extracellular matrix remodeling. In cancer, formation of invadopodia is strongly associated with invasive potential....
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434810/ https://www.ncbi.nlm.nih.gov/pubmed/22366451 http://dx.doi.org/10.1242/jcs.100834 |