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Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM). Intratumoral hypoxia is common in GBM and may be associated with the development of TMZ resistance. Oxygen therapy has previously been reported to potentiate the effect of chemotherapy in cancer. In this study, we investi...

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Detalles Bibliográficos
Autores principales:	Sun, Stella, Lee, Derek, Lee, Nikki P., Pu, Jenny K. S., Wong, Stanley T. S., Lui, W. M., Fung, C. F., Leung, Gilberto K. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434886/ https://www.ncbi.nlm.nih.gov/pubmed/22763762 http://dx.doi.org/10.1007/s11060-012-0923-3

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