Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature

A 22-year-old man was admitted to our hospital because of fever, skin rash and epistaxis. Physical examination revealed fever (39.5°C), generalized purpura, lymphadenopathy and splenomegaly. Blood tests showed pancytopenia. Bone marrow aspiration and biopsy showed hemophagocytosis with no evidence o...

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Autores principales: Koubâa, M., Marrakchi, Ch, Mâaloul, I., Makni, S., Berrajah, L., Elloumi, M., Hammami, B., Lahiani, D., Boudawara, T., Ben Jemâa, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435130/
https://www.ncbi.nlm.nih.gov/pubmed/22973494
http://dx.doi.org/10.4084/MJHID.2012.050
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author Koubâa, M.
Marrakchi, Ch
Mâaloul, I.
Makni, S.
Berrajah, L.
Elloumi, M.
Hammami, B.
Lahiani, D.
Boudawara, T.
Ben Jemâa, M.
author_facet Koubâa, M.
Marrakchi, Ch
Mâaloul, I.
Makni, S.
Berrajah, L.
Elloumi, M.
Hammami, B.
Lahiani, D.
Boudawara, T.
Ben Jemâa, M.
author_sort Koubâa, M.
collection PubMed
description A 22-year-old man was admitted to our hospital because of fever, skin rash and epistaxis. Physical examination revealed fever (39.5°C), generalized purpura, lymphadenopathy and splenomegaly. Blood tests showed pancytopenia. Bone marrow aspiration and biopsy showed hemophagocytosis with no evidence of malignant cells. Anti rubella IgM antibody were positive and the IgG titers increased from 16 to 50 UI/mL in 3 days. Therefore, he was diagnosed to have rubella-associated hemophagocytic syndrome. We report herein the first case in a man and the sixth case of rubella-associated hemophagocytic syndrome in the literature by search in Pub Med till March 2012.
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spelling pubmed-34351302012-09-12 Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature Koubâa, M. Marrakchi, Ch Mâaloul, I. Makni, S. Berrajah, L. Elloumi, M. Hammami, B. Lahiani, D. Boudawara, T. Ben Jemâa, M. Mediterr J Hematol Infect Dis Case Report A 22-year-old man was admitted to our hospital because of fever, skin rash and epistaxis. Physical examination revealed fever (39.5°C), generalized purpura, lymphadenopathy and splenomegaly. Blood tests showed pancytopenia. Bone marrow aspiration and biopsy showed hemophagocytosis with no evidence of malignant cells. Anti rubella IgM antibody were positive and the IgG titers increased from 16 to 50 UI/mL in 3 days. Therefore, he was diagnosed to have rubella-associated hemophagocytic syndrome. We report herein the first case in a man and the sixth case of rubella-associated hemophagocytic syndrome in the literature by search in Pub Med till March 2012. Università Cattolica del Sacro Cuore 2012-08-09 /pmc/articles/PMC3435130/ /pubmed/22973494 http://dx.doi.org/10.4084/MJHID.2012.050 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Koubâa, M.
Marrakchi, Ch
Mâaloul, I.
Makni, S.
Berrajah, L.
Elloumi, M.
Hammami, B.
Lahiani, D.
Boudawara, T.
Ben Jemâa, M.
Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title_full Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title_fullStr Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title_full_unstemmed Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title_short Rubella Associated with Hemophagocytic Syndrome. First Report in a Male and Review of the Literature
title_sort rubella associated with hemophagocytic syndrome. first report in a male and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435130/
https://www.ncbi.nlm.nih.gov/pubmed/22973494
http://dx.doi.org/10.4084/MJHID.2012.050
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