SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity

Phosphorylation or SUMOylation of the kainate receptor (KAR) subunit GluK2 have both individually been shown to regulate KAR surface expression. However, it is unknown if phosphorylation and SUMOylation of GluK2 are important for activity-dependent KAR synaptic plasticity. Here, we show that PKC-med...

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Detalles Bibliográficos
Autores principales: Chamberlain, Sophie E L, González-González, Inmaculada M, Wilkinson, Kevin A, Konopacki, Filip A, Kantamneni, Sriharsha, Henley, Jeremy M, Mellor, Jack R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435142/
https://www.ncbi.nlm.nih.gov/pubmed/22522402
http://dx.doi.org/10.1038/nn.3089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435142/
https://www.ncbi.nlm.nih.gov/pubmed/22522402
http://dx.doi.org/10.1038/nn.3089

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