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Dependencies among Editing Sites in Serotonin 2C Receptor mRNA
The serotonin 2C receptor (5-HT(2C)R)–a key regulator of diverse neurological processes–exhibits functional variability derived from editing of its pre-mRNA by site-specific adenosine deamination (A-to-I pre-mRNA editing) in five distinct sites. Here we describe a statistical technique that was deve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435259/ https://www.ncbi.nlm.nih.gov/pubmed/22969417 http://dx.doi.org/10.1371/journal.pcbi.1002663 |