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Dependencies among Editing Sites in Serotonin 2C Receptor mRNA

The serotonin 2C receptor (5-HT(2C)R)–a key regulator of diverse neurological processes–exhibits functional variability derived from editing of its pre-mRNA by site-specific adenosine deamination (A-to-I pre-mRNA editing) in five distinct sites. Here we describe a statistical technique that was deve...

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Detalles Bibliográficos
Autores principales: Carmel, Liran, Koonin, Eugene V., Dracheva, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435259/
https://www.ncbi.nlm.nih.gov/pubmed/22969417
http://dx.doi.org/10.1371/journal.pcbi.1002663