Cargando…

Transcriptional and Epigenetic Regulation of KIAA1199 Gene Expression in Human Breast Cancer

Emerging evidence has demonstrated that upregulated expression of KIAA1199 in human cancer bodes for poor survival. The regulatory mechanism controlling KIAA1199 expression in cancer remains to be characterized. In the present study, we have isolated and characterized the human KIAA1199 promoter in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuscu, Cem, Evensen, Nikki, Kim, Deborah, Hu, You-Jun, Zucker, Stanley, Cao, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435267/ https://www.ncbi.nlm.nih.gov/pubmed/22970280 http://dx.doi.org/10.1371/journal.pone.0044661

Ejemplares similares

Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia
por: Suh, Han Na, et al.
Publicado: (2016)

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions
por: Marella, Mathieu, et al.
Publicado: (2018)

Knockdown of KIAA1199 attenuates growth and metastasis of hepatocellular carcinoma
por: Liu, Jingmei, et al.
Publicado: (2018)

CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane
por: Deroyer, Céline, et al.
Publicado: (2022)

Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness
por: Jami, Mohammad-Saeid, et al.
Publicado: (2014)

Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerization()
por: Yoshida, Hiroyuki, et al.
Publicado: (2013)

KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer
por: Kohi, Shiro, et al.
Publicado: (2017)

Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea
por: Hosoya, Makoto, et al.
Publicado: (2016)

Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer
por: Oba, Takuya, et al.
Publicado: (2021)

KIAA1199 as a potential diagnostic biomarker of rheumatoid arthritis related to angiogenesis
por: Yang, Xinyu, et al.
Publicado: (2015)

CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes
por: Deroyer, Céline, et al.
Publicado: (2019)

Overexpression of KIAA1199 is an independent prognostic marker in laryngeal squamous cell carcinoma
por: Huang, Meixiang, et al.
Publicado: (2020)

Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma
por: Zhai, Xiangyu, et al.
Publicado: (2020)

Downregulation of KIAA1199 by miR‐486‐5p suppresses tumorigenesis in lung cancer
por: Wang, Anqi, et al.
Publicado: (2020)

Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells
por: Birkenkamp-Demtroder, K, et al.
Publicado: (2011)

Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival
por: Fink, Stephen P., et al.
Publicado: (2015)

NF-κB-induced KIAA1199 promotes survival through EGFR signalling
por: Shostak, Kateryna, et al.
Publicado: (2014)

KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment
por: Chen, Li, et al.
Publicado: (2019)

Early Insights into the Function of KIAA1199, a Markedly Overexpressed Protein in Human Colorectal Tumors
por: Tiwari, Amit, et al.
Publicado: (2013)

Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments
por: Soroosh, Artin, et al.
Publicado: (2016)

KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration
por: Chen, Li, et al.
Publicado: (2023)

Development of Therapeutic Agent for Osteoarthritis via Inhibition of KIAA1199 Activity: Effect of Ipriflavone In Vivo
por: Zhang, Jiarui, et al.
Publicado: (2023)

Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma
por: Ito, Kan, et al.
Publicado: (2021)

KIAA1199 Correlates With Tumor Microenvironment and Immune Infiltration in Lung Adenocarcinoma as a Potential Prognostic Biomarker
por: Shen, Xiaoju, et al.
Publicado: (2022)

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma
por: Jiang, Zhengchen, et al.
Publicado: (2018)

Co-expression of KIAA1199 and hypoxia-inducible factor 1α is a biomarker for an unfavorable prognosis in hepatocellular carcinoma
por: Wang, Dan, et al.
Publicado: (2020)

Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial–mesenchymal transition
por: Liu, Jingmei, et al.
Publicado: (2023)

Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression
por: Sato, Shinya, et al.
Publicado: (2023)

KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival
por: Terashima, Masato, et al.
Publicado: (2014)

Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner
por: Zhang, Wei, et al.
Publicado: (2021)

KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation
por: Hua, Qingling, et al.
Publicado: (2023)

HIF1α/CCL7/KIAA1199 axis mediates hypoxia-induced gastric cancer aggravation and glycolysis alteration
por: Mi, Chen, et al.
Publicado: (2023)

LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer
por: Sun, Junfeng, et al.
Publicado: (2018)

Role of HYBID (Hyaluronan Binding Protein Involved in Hyaluronan Depolymerization), Alias KIAA1199/CEMIP, in Hyaluronan Degradation in Normal and Photoaged Skin
por: Yoshida, Hiroyuki, et al.
Publicado: (2019)

Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)
por: Evensen, Nikki A., et al.
Publicado: (2015)

PT680. Distribution and brain function of Hyaluronan Binding Protein Involved in Hyaluronan Depolymerization (HYBID, KIAA1199) in mouse central nerve system.
por: Yoshino, Yuta, et al.
Publicado: (2016)

Retraction Note: LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer
por: Sun, Junfeng, et al.
Publicado: (2021)

KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer
por: Jia, Shuqin, et al.
Publicado: (2017)

KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT)
por: Jiao, Xuehua, et al.
Publicado: (2019)

Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase
por: Koike, Hiroshi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4nfvhgdtndebdq8ke6qg763tlm